So what is Functional Testing …

And how does it work?

Functional Testing

Functional testing is an excellent way to investigate and help identify the root causes of imbalances quickly and cost effectively but more importantly, help me put the most suitable health plan in place for your needs. Testing can quickly reveal what is happening on the inside of your body including food allergies or intolerances, nutritional deficiencies, metabolic function and hormonal imbalances.

Popular tests I regularly recommend include, but are not limited to, the following:

GI Map – Invivo Clinical – From £335
(1 stool sample, turnaround approx. 14 days).

A comprehensive stool test, perfect for those suffering from digestive complaints such as; IBS, indigestion, dysbiosis, constipation, diarrhoea, bloating, abdominal pain and autoimmunity. This test offers detailed information regarding the digestion and absorption of food in the gut, immune function, inflammation status, balance of beneficial bacteria, overgrowth of microbes including yeasts, virus’s and the presence of parasites.

ONE test (Optimal Nutritional Evaluation) Genova Diagnostics – £324
(one urine sample over one day, turnaround approx. 14 days).

This test helps to give an understanding of individual diet and supplementation needs, and offers a personalized functional nutrition assessment covering antioxidants, vitamins, minerals, digestive support and energy metabolism. Symptoms and chronic conditions related to nutritional deficiencies include; postnatal depletion, mood disorders, depression, anxiety, sleep disturbance, fibromyalgia, fatigue and metabolic imbalances.

Fertility Profile – Invivo Clinical – £290.00

(Sampling is done on days 3 and 21 of the menstrual cycle via blood spot and saliva. Turnaround approx. 14 days).

Recommended for women who have hormonal symptoms, have been trying to conceive for more than six months, are in their mid 30’s or beyond, have had past difficulty in sustaining pregnancy, know infertility runs in their family and want to assess their fertility status.

Patients can collect their samples conveniently and at the appropriate cycle times with minimal disruption to their lives and busy work schedules.

Adrenal Stress Index (ASI) Genova Diagnostics from £85 to £107
(A non-invasive salivary hormone test, 4 samples taken over one day. Turnaround approx. 14 days).

The ASI can indicate imbalances in the stress hormones cortisol and DHEA. Disruption to the normal rhythm of these hormones may have a profound effect on energy levels, emotions, and many other health complaints – including anxiety, chronic inflammatory conditions, allergies, chronic fatigue syndrome, insomnia, depression, migraines, headaches, recurrent infections, menstrual difficulties and infertility.

Thyroid panel – Genova Diagnostics – from £148
(Blood test, turnaround approx. 14 days).

A hormone test that provides a thorough analysis of thyroid hormone metabolism. It includes central thyroid gland regulation and activity, thyroid production and secretion, peripheral thyroid conversion, and thyroid autoimmunity. This hormone test allows me to pinpoint common imbalances that underlie a broad spectrum of chronic illness. This test analyses serum levels of TSH, free T4, free T3, reverse T3, anti-TG antibodies, and anti-TPO antibodies to assess central and peripheral thyroid function, as well as thyroid auto-immunity.

DUTCH complete Hormones test £286

(Clients collect just four or five dried urine samples over a 24-hour period. Turnaround approx. 14 days).

Comprehensive hormone test that measures sex hormones and stress (adrenal) hormones and their metabolites, including; progesterone, oestrogen, testosterone and cortisol.  Also includes melatonin to help identify any hormonal imbalances within your monthly cycle. Common symptoms of this can include premenstrual tension, fluid retention, excessive menstrual bleeding, menstrual irregularity, low libido, endometriosis, ovarian cysts, infertility, acne, and excess body hair.

Food intolerance testing – Cambridge Nutritional Sciences – from £111.
(Blood spot, turnaround approx. 7-14 days).

Although not life threatening like a food allergy, food intolerances should never be underestimated. Their impact on sufferers can be significant, severely impacting on their ability to live normal healthy lives. Food intolerances can lead to delayed symptoms including headaches, weight gain, inflammation and immune reactions.

Vitamin D – Cambridge Nutritional Sciences – £40

(Blood test, turnaround approx. 7-14 days).
A vitamin D test can, in some cases, be obtained via your GP, however where not available this is a reasonable alternative.

Vitamin D deficiency is becoming increasingly common within our population. It’s a powerful modulator of our immune system and acts more like a hormone than a vitamin in the body. Maintaining Vitamin D levels protects the body from a wide range of diseases including viruses, cardiovascular disease, bone disease, autoimmune disease (such as multiple sclerosis and rheumatoid arthritis), strokes, nervous system disorders (such as Parkinson’s disease) and type 1 and 2 diabetes. Depression and breast, prostate and colon cancer have also been linked to Vitamin D deficiency. It is important to know your levels before supplementing as toxicity can cause its own symptoms.

Please note all prices are subject to change.


I believe that Functional Medicine is one of the most important ideas of our time – an idea that can help relieve the unnecessary suffering of millions.

Dr Mark Hyman MD

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